In patients with COPD, how might SpO2 targets differ from typical targets?

• A. Always aim for 100%
• B. Lower targets may be used in COPD
• C. SpO2 targets are not relevant
• D. Target is 80-85%

Answer: (B)

In COPD, oxygen targets are adjusted to balance providing enough oxygen with avoiding CO2 retention. Many COPD patients chronically retain carbon dioxide; giving too much oxygen can blunt their drive to breathe and worsen hypercapnia, leading to acidosis and poorer ventilation. To prevent that, clinicians often target a modest SpO2, commonly about 88–92%, rather than aiming for normal high saturations. That’s why lower targets may be used in COPD. Aiming for 100% is not necessary and can be harmful, while 80–85% would risk inadequate oxygenation. SpO2 targets are relevant and should be tailored to the patient’s status.